Molecular Insights into Epigenetics and Cannabinoid Receptors
Abstract The actions of cannabis are mediated by G protein-coupled receptors that are part of an endogenous cannabinoid system (ECS).…
histone acetylation
Alternative Splicing, Epigenetic Modifications and Cancer: A Dangerous Triangle, or a Hopeful One?
Abstract Simple Summary: Epigenetics studies the alteration of gene expression without changing DNA sequence and very often, epigenetic dysregulation causes…
Cannabinoid exposure in rat adolescence reprograms the initial behavioral, molecular, and epigenetic response to cocaine
Abstract The endocannabinoid system has a modulatory role in brain reward and cognitive processes. It has been hypothesized that repeated…
A histone-mimicking interdomain linker in a multidomain protein modulates multivalent histone binding
Abstract N-terminal histone tails are subject to many posttranslational modifications that are recognized by and interact with designated reader domains…