heteronuclear single quantum coherence

April 20, 2022

αα-hub coregulator structure and flexibility determine transcription factor binding and selection in regulatory interactomes

Abstract Formation of transcription factor (TF)–coregulator complexes is a key step in transcriptional regulation, with coregulators having essential functions as…

April 7, 2022

The dimerization mechanism of the N-terminal domain of spider silk proteins is conserved despite extensive sequence divergence

Abstract The N-terminal (NT) domain of spider silk proteins (spidroins) is crucial for their storage at high concentrations and also…

March 18, 2022

Paip2A inhibits translation by competitively binding to the RNA recognition motifs of PABPC1 and promoting its dissociation from the poly(A) tail

Abstract Eukaryotic mRNAs possess a poly(A) tail at their 3′-end, to which poly(A)-binding protein C1 (PABPC1) binds and recruits other…

December 30, 2021

Degradation of the E. coli antitoxin MqsA by the proteolytic complex ClpXP is regulated by zinc occupancy and oxidation

Abstract It is well established that the antitoxins of toxin–antitoxin (TA) systems are selectively degraded by bacterial proteases in response…

August 17, 2021

Structural and functional variation of chitin-binding domains of a lytic polysaccharide monooxygenase from Cellvibrio japonicus

Abstract Among the extensive repertoire of carbohydrate-active enzymes, lytic polysaccharide monooxygenases (LPMOs) have a key role in recalcitrant biomass degradation.…

June 26, 2020

Yeast Spt6 Reads Multiple Phosphorylation Patterns of RNA Polymerase II C-Terminal Domain In Vitro

Abstract Transcription elongation factor Spt6 associates with RNA polymerase II (RNAP II) via a tandem SH2 (tSH2) domain. The mechanism…

December 24, 2014

Soluble cysteine-rich tick saliva proteins Salp15 and Iric-1 from E. coli

Keywords: DsbA, thiol:disulfide interchange protein DsbA, immunoglobulin binding domain B1 of streptococcal protein G, eGFP, enhanced green fluorescent protein, GST,…