White matter microstructure changes across the lifespan: a meta-analysis of longitudinal diffusion MRI studies
Abstract Background: White matter in the human brain is known to play a critical role in facilitating communication between different…
GWAS
Population genomics of a natural Cannabis sativa L. collection from Iran identifies novel genetic loci for flowering time, morphology, sex and chemotyping
Abstract Background: Future breeding and selection of Cannabis sativa L. for both drug production and industrial purposes require a source…
Genome-wide association study reveals the underlying regulatory mechanisms of red blood traits in Anadara granosa
Abstract Background: Anadara granosa, commonly known as the blood clam, exhibits the unusual characteristic of having red blood among invertebrates.…
Causal effect of thyroid cancer on secondary primary malignancies: findings from the UK Biobank and FinnGen cohorts
Abstract Background: Existing epidemiological data indicated a correlation between thyroid cancer (THCA) and the risk of secondary primary malignancies (SPMs).…
Multidimensional data analysis revealed thyroiditis-associated TCF19 SNP rs2073724 as a highly ranked protective variant in thyroid cancer
Abstract Background: Thyroid cancer represents the most prevalent malignant endocrine tumour, with rising incidence worldwide and high mortality rates among…
Integrative Analysis of Proteome-wide Association Studies and Functional Enrichment Analysis to Identify Genes and Chemicals Associated with Alcohol Dependence
Abstract Methods: Using data from published alcohol dependence genome-wide association studies, we first conducted a proteome-wide association study of alcohol…
Genome-wide association study for systemic lupus erythematosus in an egyptian population
Abstract Systemic lupus erythematosus (SLE) susceptibility has a strong genetic component. Genome-wide association studies (GWAS) across trans-ancestral populations show both…
The Cannabis-Induced Epigenetic Regulation of Genes Associated with Major Depressive Disorder
Abstract The prevalence of depression is increasing worldwide, as is the number of people suffering from treatment-resistant depression; these patients…
Genetic Architecture of Flowering Time and Sex Determination in Hemp (Cannabis sativa L.): A Genome-Wide Association Study
Abstract Flowering time and sex determination in hemp (Cannabis sativa L.) strongly influence fiber quality and seed production of this…
Elucidating the Genetic Architecture of Fiber Quality in Hemp (Cannabis sativa L.) Using a Genome-Wide Association Study
Abstract Hemp (Cannabis sativa L.) is a bast-fiber crop with a great potential in the emerging bio-based economy. Yet, hemp…