Current Challenges and Future Directions in the Assessment of Glucocorticoid Status
Abstract Glucocorticoid (GC) hormones are secreted in a circadian and ultradian rhythm and play a critical role in maintaining physiological…
glucocorticoid receptor
The Glucocorticoid Receptor: Isoforms, Functions, and Contribution to Glucocorticoid Sensitivity
Abstract Glucocorticoids exert pleiotropic effects on all tissues to regulate cellular and metabolic homeostasis. Synthetic forms are used therapeutically in…
The Pathways between Cortisol-Related Regulation Genes and PTSD Psychotherapy
Abstract Post-traumatic stress disorder (PTSD) only develops after exposure to a traumatic event in some individuals. PTSD can be chronic…
A General Introduction to Glucocorticoid Biology
Abstract Glucocorticoids (GCs) are steroid hormones widely used for the treatment of inflammation, autoimmune diseases, and cancer. To exert their…
The HPA – Immune Axis and the Immunomodulatory Actions of Glucocorticoids in the Brain
Abstract In response to physiological and psychogenic stressors, the hypothalamic–pituitary–adrenal (HPA) axis orchestrates the systemic release of glucocorticoids (GCs). By…