Abstract The intricacies of tumour microenvironment, particularly the extracellular matrix (ECM), underscore its pivotal function in modulating tumour progression and…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-024-83714-8. Article type: Research Article Keywords: NET1, Pan-cancer, Prognosis,…
Abstract Interferon regulatory factor 1 (IRF1) significantly affects tumour occurrence and development. This study aimed to analyse its function as…
Abstract A hyperactive tumour microenvironment (TME) drives unrestricted cancer cell survival, drug resistance, and metastasis in ovarian carcinoma (OC). However,…
Abstract Troponin T1 (TNNT1) plays a crucial role in muscle contraction but its role in cancer, particularly in kidney renal…
Abstract The highly aggressive and invasive glioblastoma (GBM) tumour is the most malignant lesion among adult-type diffuse gliomas, representing the…
Abstract IRF family genes have been shown to be crucial in tumorigenesis and tumour immunity. However, information about the role…
Abstract Simple Summary: Basal cell carcinoma is the most common human cancer. Most BCCs are low-risk and are easily treated;…
Abstract Necroptosis is a unique programmed death mechanism of necrotic cells. However, its role and specific mechanism in cancer remain…
Abstract 2′,5′-oligoadenylate synthase (OAS) is a class of enzymes induced by interferons and mainly encoded by the OAS1, OAS2, and…