FN1 Immunoregulation in Glioblastoma: Insights From Neutrophil‐Centric Studies
Abstract Neutrophils, as key components of the tumor microenvironment, play a crucial role in cancer progression and prognosis. This study…
glioblastoma multiforme
Pan-cancer analysis of the role of α2C-adrenergic receptor (ADRA2C) in human tumors and validation in glioblastoma multiforme models
Abstract Background: Several studies have reported the relationship between α2C-adrenergic receptor (ADRA2C) and both neoplastic and non-neoplastic diseases. However, a…
Pan-cancer analysis reveals the potential of hyaluronate synthase as therapeutic targets in human tumors
Abstract Hyaluronic acid (HA) is a crucial component of the extracellular matrix, and its level of accumulation is related to…
Synthesis and Significance of Arachidonic Acid, a Substrate for Cyclooxygenases, Lipoxygenases, and Cytochrome P450 Pathways in the Tumorigenesis of Glioblastoma Multiforme, Including a Pan-Cancer Comparative Analysis
Abstract Simple Summary: Glioblastoma multiforme is a brain tumor with a very unfavorable prognosis, where the vast majority of patients…
Pan-cancer analysis of ASB3 and the potential clinical implications for immune microenvironment of glioblastoma multiforme
Abstract Background: Ankyrin repeat and SOCS Box containing 3 (ASB3) is an E3 ubiquitin ligase. It has been reported to…
Comprehensive analysis of tumor necrosis factor-α-inducible protein 8-like 2 (TIPE2): A potential novel pan-cancer immune checkpoint
Keywords: LAML, Acute Myeloid Leukemia, BLCA, Bladder Urothelial Carcinoma, BRCA, Breast invasive carcinoma, CESC, Cervical squamous cell carcinoma and endocervical…
Contribution of the Testosterone Androgen Receptor–PARD3B Signaling Axis to Tumorigenesis and Malignance of Glioblastoma Multiforme through Stimulating Cell Proliferation and Colony Formation
Abstract Background: Glioblastoma multiforme (GBM) is the most common and malignant brain tumor with very poor prognoses. After surgical resection…
Comprehensive analysis of the novel omicron receptor AXL in cancers
Keywords: COVID-19, coronavirus disease 2019, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, ACE2, angiotensin-converting enzyme 2, AXL, anexelekto, UMAP, uniform…
Identifies microtubule-binding protein CSPP1 as a novel cancer biomarker associated with ferroptosis and tumor microenvironment
Keywords: TME, tumor microenvironment, CAF, cancer-associated fibroblasts, EMT, epithelial-mesenchymal transition, DLBC, diffuse large B-cell lymphoma, TCGA, The Cancer Genome Atlas,…
Identification of SHCBP1 as a potential biomarker involving diagnosis, prognosis, and tumor immune microenvironment across multiple cancers
Keywords: AUC, area under the curve, CCLE, cancer cell line encyclopedia, HR, hazard ratio, ROC, receiver operating characteristic, SHCBP1, Shc…