THC Reduces Ki67-Immunoreactive Cells Derived from Human Primary Glioblastoma in a GPR55-Dependent Manner
Abstract Simple Summary: Glioblastoma (GBM) is the most frequent primary brain tumor entity with poor prognosis and resistance to current…
glioblastoma (GBM)
A pan-cancer analysis of HER2 index revealed transcriptional pattern for precise selection of HER2-targeted therapy
Abstract Background: The prevalence of HER2 alterations in pan-cancer indicates a broader range of application of HER2-targeted therapies; however, biomarkers…
Integrative omics analysis reveals relationships of genes with synthetic lethal interactions through a pan-cancer analysis
Keywords: ACC, adrenocortical carcinoma, BLCA, bladder urothelial carcinoma, BRCA, breast invasive carcinoma, CESC, cervical squamous cell carcinoma and endocervical adenocarcinoma,…
Rewired functional regulatory networks among miRNA isoforms (isomiRs) from let-7 and miR-10 gene families in cancer
Keywords: ACC, adrenocortical carcinoma, BLCA, bladder urothelial carcinoma, BRCA, breast invasive carcinoma, CESC, cervical squamous cell carcinoma and endocervical adenocarcinoma,…
PreMSIm: An R package for predicting microsatellite instability from the expression profiling of a gene panel in cancer
Keywords: Cancer, Microsatellite instability, Gene expression profiling, Machine learning, Algorithm, Classification, AUC, area under the curve, CV, cross validation, GEO,…
Cannabinoids in Glioblastoma Therapy: New Applications for Old Drugs
Abstract Glioblastoma (GBM) is the most malignant brain tumor and one of the deadliest types of solid cancer overall. Despite…
Role of Redox Status in Development of Glioblastoma
Abstract Glioblastoma multiforme (GBM) is a highly aggressive neoplasia, prognosis remains dismal, and current therapy is mostly palliative. There are…
Loss of TRPV2 Homeostatic Control of Cell Proliferation Drives Tumor Progression
Abstract Herein we evaluate the involvement of the TRPV2 channel, belonging to the Transient Receptor Potential Vanilloid channel family (TRPVs),…