Obtaining spatially resolved tumor purity maps using deep multiple instance learning in a pan-cancer study
Abstract Tumor purity is the percentage of cancer cells within a tissue section. Pathologists estimate tumor purity to select samples…
Genomic sequencing centers
Substantial batch effects in TCGA exome sequences undermine pan-cancer analysis of germline variants
Abstract Background: In recent years, research on cancer predisposition germline variants has emerged as a prominent field. The identity of…