Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-05997-9. Article type: Research Article Keywords: Peptidyl-prolyl cis-trans isomerase…
Abstract Tau (MAPT) is a microtubule-associated protein causing common neurodegenerative diseases or rare inherited frontotemporal lobar degenerations. Emerging evidence for…
Abstract Somatic mutations occur as random genetic changes in genes through protein-affecting mutations (PAMs), gene fusions, or copy number alterations…
Abstract A cancer immune phenotype characterized by an active T-helper 1 (Th1)/cytotoxic response is associated with responsiveness to immunotherapy and…
Abstract Studies describing the expression patterns and biomarkers for the tumoral process increase in number every year. The availability of…
Abstract Isoform switching is a recently characterized hallmark of cancer, and often translates to the loss or gain of domains…
Abstract RNA Binding Proteins (RBPs) are a class of post-transcriptional regulatory molecules which are increasingly documented to be dysfunctional in…