The Interplay between the Immune and the Endocannabinoid Systems in Cancer
Abstract The therapeutic potential of Cannabis sativa has been recognized since ancient times. Phytocannabinoids, endocannabinoids and synthetic cannabinoids activate two…
Gene regulation in immune cells
The Immune Endocannabinoid System of the Tumor Microenvironment
Abstract Leukocytes are part of the tumor microenvironment (TME) and are critical determinants of tumor progression. Because of the immunoregulatory…
Endocannabinoids as Guardians of Metastasis
Abstract Endocannabinoids including anandamide and 2-arachidonoylglycerol are involved in cancer pathophysiology in several ways, including tumor growth and progression, peritumoral…