Actin like 6A is a prognostic biomarker and associated with immune cell infiltration in cancers
Abstract Purpose: To investigate the role of Actin like 6 A (ACTL6A) in cancer and explore the potential mechanism of…
Gene amplification
Cancer genomes tolerate deleterious coding mutations through somatic copy number amplifications of wild-type regions
Abstract Cancers evolve under the accumulation of thousands of somatic mutations and chromosomal aberrations. While most coding mutations are deleterious,…