Abstract Background: Corticobasal degeneration (CBD) presents with a range of clinical phenotypes, making diagnosis challenging. We report the clinical course…
Abstract Dysregulation of the complement system plays an important role in the pathogenesis of neurodegenerative diseases, including Alzheimer’s disease (AD).…
Abstract (1) Background: Frontotemporal lobar degeneration (FTLD) is a generic term which refers to multiple pathologies, including FTLD-tau. The most…
Abstract Background: Frontotemporal disorders (FTD) are the consequence of impairment to neurons in the frontal and temporal lobes of the…
Abstract Background: Alzheimer’s disease dementia (ADD) may manifest with atypical phenotypes, resembling behavioral variant frontotemporal dementia (bvFTD) and corticobasal syndrome…
Abstract One of the defining pathological features of Alzheimer’s disease (AD) is the deposition of neurofibrillary tangles (NFTs) composed of…
Abstract Thalamic atrophy is a common feature across all forms of FTD but little is known about specific nuclei involvement.…
Abstract Frontotemporal dementia (FTD) syndromes comprise a heterogeneous group of neurodegenerative conditions characterized by atrophy in the frontal and temporal…
Abstract Microtubules are key cytoskeletal elements found in all eukaryotic cells. The microtubule shaft is composed of the heterodimer protein,…