Hypothalamic cannabinoid signaling: Consequences for eating behavior
Abstract In parallel to the legalization of cannabis for both medicinal and recreational purposes, cannabinoid use has steadily increased over…
food intake
Novel GPR18 Ligands in Rodent Pharmacological Tests: Effects on Mood, Pain, and Eating Disorders
Abstract The lack of selective pharmacological tools has limited the full unraveling of G protein-coupled receptor 18 (GPR18) functions. The…
Endocannabinoids and the Gut-Brain Control of Food Intake and Obesity
Abstract Gut-brain signaling controls food intake and energy homeostasis, and its activity is thought to be dysregulated in obesity. We…
Discovery of Orexant and Anorexant Agents with Indazole Scaffold Endowed with Peripheral Antiedema Activity
Abstract The endocannabinoid system represents an integrated neuronal network involved in the control of several organisms’ functions, such as feeding…
Behavioral effects of the cannabinoid CB1 receptor allosteric modulator ORG27569 in rats
Abstract The cannabinoid CB1 receptor system is involved in feeding behaviors and the CB1 receptor antagonist SR141716A is an effective…
Effects of glucagon-like peptide-1 receptor stimulation and blockade on food consumption and body weight in rats treated with a cannabinoid CB1 receptor agonist WIN 55,212-2
Abstract Background: Glucagon-like peptide-1 (GLP-1) and endocannabinoids are involved in appetite control. Recently we have demonstrated that cannabinoid (CB)1 receptor…