Cannabis Use and Resting State Functional Connectivity in the Aging Brain
Abstract Several lines of evidence suggest that older adults (aged 65+) sharply increased their cannabis use over the last decade,…
fMRI
Interaction of sex and cannabis in adult in vivo brain imaging studies: A systematic review
Abstract Cannabis has been shown to cause structural and functional neurocognitive changes in heavy users. Cannabis use initiation aligns with…
Epigenetic Mediation of AKT1 rs1130233’s Effect on Delta-9-Tetrahydrocannabinol-Induced Medial Temporal Function during Fear Processing
Abstract High doses of delta-9-tetrahydrocannabinol (THC), the main psychoactive component of cannabis, have been shown to have anxiogenic effects. Additionally,…
Patterns of brain function associated with cannabis cue-reactivity in regular cannabis users: a systematic review of fMRI studies
Abstract Rationale: Regular cannabis use (i.e. ≥ monthly) is highly prevalent, with past year use being reported by ~ 200…
Cannabidiol and the corticoraphe circuit in post-traumatic stress disorder
Abstract Post-Traumatic Stress Disorder (PTSD), characterized by re-experiencing, avoidance, negative affect, and impaired memory processing, may develop after traumatic events.…
The Impact of THC and CBD in Schizophrenia: A Systematic Review
Abstract Background: People with schizophrenia are more likely to develop cannabis use disorder (CUD) and experience worse outcomes with use.…
Cannabinoids, reward processing, and psychosis
Abstract Background: Evidence suggests that an overlap exists between the neurobiology of psychotic disorders and the effects of cannabinoids on…
Does Chronic Cannabis Use Impact Risky Decision-Making: An Examination of fMRI Activation and Effective Connectivity?
Abstract With the increase in use of cannabis and its shifting legal status in the United States, cannabis use has…
Ibudilast for alcohol use disorder: study protocol for a phase II randomized clinical trial
Abstract Background: Alcohol use disorder (AUD) is a chronic and relapsing condition for which current pharmacological treatments are only modestly…
Unraveling the role of cigarette use in neural cannabis cue reactivity in heavy cannabis users
Abstract Cue reactivity is an important biomarker of cannabis use disorder (CUD). Despite high rates of cigarette and cannabis co‐use,…