Cannabinoids, Phenolics, Terpenes and Alkaloids of Cannabis
Abstract Cannabis sativa is one of the oldest medicinal plants in the world. It was introduced into western medicine during…
flavonoids
Non-Cannabinoid Metabolites of Cannabis sativa L. with Therapeutic Potential
Abstract The cannabis plant (Cannabis sativa L.) produces an estimated 545 chemical compounds of different biogenetic classes. In addition to…
Evolution of the Polyphenol and Terpene Content, Antioxidant Activity and Plant Morphology of Eight Different Fiber-Type Cultivars of Cannabis sativa L. Cultivated at Three Sowing Densities
Abstract The chemical composition of the inflorescences of eight different fibre-type Cannabis sativa L. cultivars grown in Switzerland was monitored…
In Silico Identification of MYB and bHLH Families Reveals Candidate Transcription Factors for Secondary Metabolic Pathways in Cannabis sativa L.
Abstract Plant secondary metabolic pathways are finely regulated by the activity of transcription factors, among which members of the bHLH…
Natural Compounds as Guides for the Discovery of Drugs Targeting G-Protein-Coupled Receptors
Abstract G protein-coupled receptors (GPCRs), which constitute the most populous family of the human proteome, are the target of 35–45%…
Anti-Cancer Potential of Cannabinoids, Terpenes, and Flavonoids Present in Cannabis
Abstract In recent years, and even more since its legalization in several jurisdictions, cannabis and the endocannabinoid system have received…
New Methods for the Comprehensive Analysis of Bioactive Compounds in Cannabis sativa L. (hemp)
Abstract Cannabis sativa L. is a dioecious plant belonging to the Cannabaceae family. The main phytochemicals that are found in…
Antioxidative Polyphenols from Defatted Oilseed Cakes: Effect of Solvents
Abstract Defatted hemp, flax and canola seed cakes were extracted with different solvent systems namely methanol, ethanol, acetone, methanol 80%,…
Cytochrome P450 Family 1 Inhibitors and Structure-Activity Relationships
Abstract With the widespread use of O-alkoxyresorufin dealkylation assays since the 1990s, thousands of inhibitors of cytochrome P450 family 1…