Abstract Tumor matrix stiffness plays a critical role in cancer progression, metastasis, and therapy resistance. Although traditional biophysical methods have…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s13353-025-00970-8. Article type: Research Article Keywords: CBD, Hypothalamic neurons,…
Abstract Hepatic fibrosis is a consequence of liver injuries, in which the overproduction and progressive accumulation of extracellular matrix (ECM)…
Abstract Hyaluronic acid (HA) is a crucial component of the extracellular matrix, and its level of accumulation is related to…
Abstract The desmoplastic reaction observed in many cancers is a hallmark of disease progression and prognosis, particularly in breast and…
Abstract Alternatively spliced forms of fibronectin, called oncofetal fibronectin, are aberrantly expressed in cancer, with little to no expression in…
Abstract Background: Gastric cancer is one of the deadliest cancers, currently available therapies have limited success. Cancer-associated fibroblasts (CAFs) are…
Abstract Background: Thrombospondin-2 (THBS2) is a versatile glycoprotein that regulates numerous biological functions, including the apoptosis-proliferation balance in endothelial cells,…
Abstract Pulmonary fibrosis (PF) is a severe respiratory disease caused by lung microenvironment changes. TGF-β/Smad3 signaling pathway plays a critical…