Biobanks, offspring fitness and the influence of developmental plasticity in conservation biology
Abstract Mitigation of the widely known threats to the world’s biodiversity is difficult, despite the strategies and actions proposed by…
extinction
Enhancing Psychological Interventions for Post-Traumatic Stress Disorder (PTSD) Treatment with Memory Influencing Drugs
Abstract Post-traumatic stress disorder (PTSD) is a chronic psychiatric disease resulting from the experience or witnessing of traumatic events. Persistent…
Cannabidiol Prevents Spontaneous Fear Recovery after Extinction and Ameliorates Stress-Induced Extinction Resistance
Abstract Cannabidiol, the main non-psychotropic constituent of cannabis, has potential as a treatment for anxiety-related disorders since it reduces learned…
Comparison of cannabidiol to citalopram in targeting fear memory in female mice
Abstract Background: Cannabidiol (CBD) and selective serotonin reuptake inhibitors (SSRIs) are currently used to treat post-traumatic stress disorder (PTSD). However,…
Cannabinoid Regulation of Fear and Anxiety: an Update
Abstract Purpose of Review: Anxiety- and trauma-related disorders are prevalent and debilitating mental illnesses associated with a significant socioeconomic burden.…
Inhibition of Diacylglycerol Lipase Impairs Fear Extinction in Mice
Abstract Elucidating the underlying molecular mechanisms regulating fear and extinction learning may offer insights that can lead to novel treatments…
Bidirectional Effects of Cannabidiol on Contextual Fear Memory Extinction
Abstract Cannabidiol (CBD) has been established to have both acute and long-lasting effects to reduce fear memory expression. The long-lasting…
Cannabidiol Regulation of Learned Fear: Implications for Treating Anxiety-Related Disorders
Abstract Anxiety and trauma-related disorders are psychiatric diseases with a lifetime prevalence of up to 25%. Phobias and post-traumatic stress…
The Role of Cannabinoids in Modulating Emotional and Non-Emotional Memory Processes in the Hippocampus
Abstract Cannabinoid agonists generally have a disruptive effect on memory, learning, and operant behavior that is considered to be hippocampus-dependent.…