experimental autoimmune encephalomyelitis

February 1, 2019

Regulatory effects of hemp seed/evening primrose oil supplement in comparison with rapamycin on the expression of the mammalian target of rapamycin-complex 2 and interleukin-10 genes in experimental autoimmune encephalomyelitis

Abstract The mammalian target of rapamycin (mTOR) signaling plays a critical role in lipid synthesis and immune responses. The T…

December 1, 2018

The potential effects of hemp seed/evening primrose oils on the mammalian target of rapamycin complex 1 and interferon-gamma genes expression in experimental autoimmune encephalomyelitis

Abstract The mammalian target of rapamycin (mTOR) has a fundamental role in the metabolism, growth, and regulation of the immune…

August 3, 2018

Cannabidiol Attenuates Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis Through Induction of Myeloid-Derived Suppressor Cells

Abstract Multiple sclerosis (MS) is a chronic debilitating autoimmune disease without a cure. While the use of marijuana cannabinoids for…

September 2, 2016

Interaction between interleukin-1β and type-1 cannabinoid receptor is involved in anxiety-like behavior in experimental autoimmune encephalomyelitis

Abstract Background: Mood disorders, including anxiety and depression, are frequently diagnosed in multiple sclerosis (MS) patients, even independently of the…

November 14, 2013

Multiple sclerosis-induced neuropathic pain: pharmacological management and pathophysiological insights from rodent EAE models

Abstract In patients with multiple sclerosis (MS), pain is a frequent and disabling symptom. The prevalence is in the range…