Abstract Background/Objectives: Colorectal cancer (CRC) remains a significant global health concern, with limited treatment options for metastatic stage 4 CRC.…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-12619-x. Article type: Research Article Keywords: UGGT1, Cancer, Biomarker,…
Abstract Antineoplastic agents can induce tissue damage through oxidative stress mechanisms. Doxorubicin, a widely used chemotherapeutic agent, has been shown…
Abstract Background/Objectives: Activation of cannabinoid CB1 or CB2 receptors induces the death of glial progenitors from the chick retina in…
Abstract The endoplasmic reticulum (ER) is the organelle mainly involved in maintaining cellular homeostasis and driving correct protein folding. ER-dependent…
Abstract Background: Recent studies suggested that individuals with metabolic disorders have altered function of adipocytes and adipose stem cell subpopulations,…
Keywords: Δ, ER stress, Macropinocytosis, AMPK, HL-1 cells Authors: Tatsuhiko Murata, Kanako Noritake, Toshihiko Aki, Koichi Uemura License: © 2021…
Abstract The protective effect of cannabidiol (CBD), the non-psychoactive component of Cannabis sativa, against neuronal toxicity induced by cadmium chloride…
Abstract Cannabidiol (CBD) is the most abundant cannabinoid in Cannabis sativa that has no psychoactive properties. CBD has been approved…
Abstract Gemcitabine (GEM, 2′,2′-difluorodeoxycytidine) is currently used in advanced pancreatic adenocarcinoma, with a response rate of < 20%. The purpose…