A Volumetric Absorptive Microsampling Technique to Monitor Cannabidiol Levels in Epilepsy Patients
Abstract Purpose: Interest in cannabis-based therapies has recently increased, due to the availability of cannabidiol (CBD) for the treatment of…
epilepsy
Cannabinoids for People with ASD: A Systematic Review of Published and Ongoing Studies
Abstract The etiopathogenesis of autism spectrum disorder (ASD) remains largely unclear. Among other biological hypotheses, researchers have evidenced an imbalance…
Drug-Drug Interactions Between Cannabidiol and Lithium
Abstract Epidiolex® (Cannabidiol- CBD) is approved for epilepsy associated with Dravet syndrome (DS) and Lennox-Gastaut syndrome (LGS) in patients over…
Receptors and Channels Possibly Mediating the Effects of Phytocannabinoids on Seizures and Epilepsy
Abstract Epilepsy contributes to approximately 1% of the global disease burden. By affecting especially young children as well as older…
Report of a 6-month-old Asian infant with early infantile epileptic encephalopathy whose seizures were eliminated by cannabidiol
Abstract We observed that cannabidiol supplements were highly effective in treating an infant boy with drug-resistant early infantile epileptic encephalopathy,…
Phenotype-Based Screening of Synthetic Cannabinoids in a Dravet Syndrome Zebrafish Model
Abstract Dravet syndrome is a catastrophic epilepsy of childhood, characterized by cognitive impairment, severe seizures, and increased risk for sudden…
Epidiolex as adjunct therapy for treatment of refractory epilepsy: a comprehensive review with a focus on adverse effects
Abstract Medically refractory epilepsy remains an area of intense clinical and scientific interest since a significant porportion of patients continue…
Potential Clinical Benefits of CBD-Rich Cannabis Extracts Over Purified CBD in Treatment-Resistant Epilepsy: Observational Data Meta-analysis
Abstract This meta-analysis paper describes the analysis of observational clinical studies on the treatment of refractory epilepsy with cannabidiol (CBD)-based…
Cannabinoids in the Treatment of Epilepsy: Hard Evidence at Last?
Abstract The interest in cannabis-based products for the treatment of refractory epilepsy has skyrocketed in recent years. Marijuana and other…