Patient-Derived Mutant Forms of NFE2L2/NRF2 Drive Aggressive Murine Hepatoblastomas
Abstract Background & Aims: Hepatoblastoma (HB), the most common pediatric liver cancer, often bears β-catenin mutations and deregulates the Hippo…
Abstract Background & Aims: Hepatoblastoma (HB), the most common pediatric liver cancer, often bears β-catenin mutations and deregulates the Hippo…
Abstract Alzheimer’s disease (AD) is a neurodegenerative disorder which accounts for 60–70% of the 50 million worldwide cases of dementia…
Abstract Background: Because of their low levels of expression and the inadequacy of current research tools, CB2 cannabinoid receptors (CB2R)…
Keywords: DsbA, thiol:disulfide interchange protein DsbA, immunoglobulin binding domain B1 of streptococcal protein G, eGFP, enhanced green fluorescent protein, GST,…
Abstract Monoacylglycerols (MAGs) are short-lived intermediates of glycerolipid metabolism. Specific molecular species, such as 2-arachidonoylglycerol, which is a potent activator…