Hypothalamic cannabinoid signaling: Consequences for eating behavior
Abstract In parallel to the legalization of cannabis for both medicinal and recreational purposes, cannabinoid use has steadily increased over…
Energy balance
Energy performance of compressed biomethane gas production from co-digestion of Salix and dairy manure: factoring differences between Salix varieties
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s13068-023-02412-1. Article type: Research Article Keywords: Energy analysis, Biogas,…
Hypothalamic endocannabinoids in obesity: an old story with new challenges
Abstract The crucial role of the hypothalamus in the pathogenesis of obesity is widely recognized, while the precise molecular and…
High fat-fed GPR55 null mice display impaired glucose tolerance without concomitant changes in energy balance or insulin sensitivity but are less responsive to the effects of the cannabinoids rimonabant or Δ(9)-tetrahydrocannabivarin on weight gain
Abstract Background: The insulin-sensitizing phytocannabinoid, Δ(9)-tetrahydrocannabivarin (THCV) can signal partly via G-protein coupled receptor-55 (GPR55 behaving as either an agonist…
Countering the Modern Metabolic Disease Rampage With Ancestral Endocannabinoid System Alignment
Abstract When primitive vertebrates evolved from ancestral members of the animal kingdom and acquired complex locomotive and neurological toolsets, a…
Cannabinoid-hypocretin cross-talk in the central nervous system: what we know so far
Abstract Emerging findings suggest the existence of a cross-talk between hypocretinergic and endocannabinoid systems. Although few studies have examined this…
The cannabinoid Δ9-tetrahydrocannabivarin (THCV) ameliorates insulin sensitivity in two mouse models of obesity
Abstract Background: Cannabinoid type-1 (CB1) receptor inverse agonists improve type 2 diabetes and dyslipidaemia but were discontinued due to adverse…
The Endocannabinoid System as Pharmacological Target Derived from Its CNS Role in Energy Homeostasis and Reward. Applications in Eating Disorders and Addiction
Abstract The endocannabinoid system (ECS) has been implicated in many physiological functions, including the regulation of appetite, food intake and…