Beta-Caryophyllene, a Cannabinoid Receptor Type 2 Selective Agonist, in Emotional and Cognitive Disorders
Abstract Mental disorders account for one of the most prevalent categories of the burden of disease worldwide, with depression expected…
endocannabinoid system
Cannabidiol Disrupts Mitochondrial Respiration and Metabolism and Dysregulates Trophoblast Cell Differentiation
Abstract Trophoblast differentiation is a crucial process in the formation of the placenta where cytotrophoblasts (CTs) differentiate and fuse to…
Sleep, Glial Function, and the Endocannabinoid System: Implications for Neuroinflammation and Sleep Disorders
Abstract The relationship between sleep, glial cells, and the endocannabinoid system represents a multifaceted regulatory network with profound implications for…
Roadmap for the expression of canonical and extended endocannabinoid system receptors and metabolic enzymes in peripheral organs of preclinical animal models
Abstract The endocannabinoid system is widely expressed throughout the body and is comprised of receptors, ligands, and enzymes that maintain…
The effect of cannabinoids on wound healing: A review
Abstract Background and Aims: Cannabis and its various derivatives are commonly used for both recreational and medicinal purposes. Cannabinoids have…
Osteopathic Approach in the Stimulation of the Endocannabinoid System: A Case Report
Abstract The endocannabinoid system is an important neuromodulatory system responsible for maintaining homeostasis in the biological system. Similarly, the autonomic…
In silico analyses of the involvement of GPR55, CB1R and TRPV1: response to THC, contribution to temporal lobe epilepsy, structural modeling and updated evolution
Abstract Introduction: The endocannabinoid (eCB) system is named after the discovery that endogenous cannabinoids bind to the same receptors as…
Targeting the Endocannabinoid System Present in the Glioblastoma Tumour Microenvironment as a Potential Anti-Cancer Strategy
Abstract The highly aggressive and invasive glioblastoma (GBM) tumour is the most malignant lesion among adult-type diffuse gliomas, representing the…
Suppression of neuropathic pain in the circadian clock–deficient Per2m/m mice involves up-regulation of endocannabinoid system
Abstract Neuropathic pain often results from injuries and diseases that affect the somatosensory system. Disruption of the circadian clock has…
The Effect of Oil-Based Cannabis Extracts on Metabolic Parameters and Microbiota Composition of Mice Fed a Standard and a High-Fat Diet
Abstract The prevalence of obesity and obesity-related pathologies is lower in frequent cannabis users compared to non-users. It is well…