Intracellular Peptides in Cell Biology and Pharmacology
Abstract Intracellular peptides are produced by proteasomes following degradation of nuclear, cytosolic, and mitochondrial proteins, and can be further processed…
endocannabinoid system
Treatment of Fragile X Syndrome with Cannabidiol: A Case Series Study and Brief Review of the Literature
Abstract Fragile X syndrome (FXS) is an X-linked dominant disorder caused by a mutation in the fragile X mental retardation…
The Endocannabinoid System and Cannabidiol’s Promise for the Treatment of Substance Use Disorder
Abstract Substance use disorder is characterized by repeated use of a substance, leading to clinically significant distress, making it a…
Cannabidiol enhancement of exposure therapy in treatment refractory patients with phobias: study protocol of a randomized controlled trial
Abstract Background: Phobic anxiety disorders are among the most prevalent psychiatric disorders and are burdensome in terms of loss of…
Modulation of the Cannabinoid System: A New Perspective for the Treatment of the Alzheimer’s Disease
Abstract The pathogenesis of Alzheimer’s disease (AD) is somewhat complex and has yet to be fully understood. As the ef-fectiveness…
Lower circulating endocannabinoid levels in children with autism spectrum disorder
Abstract Background: The endocannabinoid system (ECS) is a major regulator of synaptic plasticity and neuromodulation. Alterations of the ECS have…
Modulation of the Endocannabinoid System Following Central Nervous System Injury
Abstract Central nervous system (CNS) injury, such as stroke or trauma, is known to increase susceptibility to various infections that…
The role of the endocannabinoid system in female reproductive tissues
Abstract There has been increasing interest in the role of endocannabinoids as critical modulators of the female reproductive processes. Endocannabinoids…
Some Prospective Alternatives for Treating Pain: The Endocannabinoid System and Its Putative Receptors GPR18 and GPR55
Abstract Background: Marijuana extracts (cannabinoids) have been used for several millennia for pain treatment. Regarding the site of action, cannabinoids…
A Systematic Review on the Pharmacokinetics of Cannabidiol in Humans
Abstract Background: Cannabidiol is being pursued as a therapeutic treatment for multiple conditions, usually by oral delivery. Animal studies suggest…