Endocannabinoid and dopaminergic system: the pas de deux underlying human motivation and behaviors
Abstract Endocannabinoid system (ECS) has been identified ever since cannabinoid, an active substance of Cannabis, was known to interact with…
endocannabinoid system
Cannabinoid Signalling in Immune–Reproductive Crosstalk during Human Pregnancy
Abstract Despite the intricate involvement of the endocannabinoid system in various physiological processes, it remains one of the most under-studied…
Cannabinoid Receptor Modulation of Neurogenesis: ST14A Striatal Neural Progenitor Cells as a Simplified In Vitro Model
Abstract The endocannabinoid system (ECS) is involved in the modulation of several basic biological processes, having widespread roles in neurodevelopment,…
THC Reduces Ki67-Immunoreactive Cells Derived from Human Primary Glioblastoma in a GPR55-Dependent Manner
Abstract Simple Summary: Glioblastoma (GBM) is the most frequent primary brain tumor entity with poor prognosis and resistance to current…
Targeting the Endocannabinoid System in Borderline Personality Disorder: Corticolimbic and Hypothalamic Perspectives
Abstract Borderline Personality Disorder (BPD) is a chronic debilitating psychiatric disorder characterized mainly by emotional instability, chaotic interpersonal relationships, cognitive…
SGIP1 is involved in regulation of emotionality, mood, and nociception and modulates in vivo signalling of cannabinoid CB1 receptors
Abstract Background and Purpose: Src homology 3‐domain growth factor receptor‐bound 2‐like endophilin interacting protein 1 (SGIP1) interacts with cannabinoid CB1…
The Endocannabinoid System Contributes to Electroacupuncture Analgesia
Abstract The extensive involvement of the endocannabinoid system (ECS) in vital physiological and cognitive processes of the human body has…
Cannabinoids in Audiogenic Seizures: From Neuronal Networks to Future Perspectives for Epilepsy Treatment
Abstract Cannabinoids and Cannabis-derived compounds have been receiving especial attention in the epilepsy research scenario. Pharmacological modulation of endocannabinoid system’s…
Targeting the endocannabinoid system for management of HIV-associated neuropathic pain: A systematic review
Abstract Human immunodeficiency virus (HIV) infection and antiretroviral therapy can independently induce HIV-associated neuropathic pain (HIV-NP). There is a dearth…
Cannabinoid and Cannabinoid-Related Receptors in the Myenteric Plexus of the Porcine Ileum
Abstract Simple Summary: The endocannabinoid system (ECS) has opened the door to novel therapeutical approaches targeting cancer, pain, anxiety, stress,…