Cannabinoid and Cannabinoid-Related Receptors in the Myenteric Plexus of the Porcine Ileum
Abstract Simple Summary: The endocannabinoid system (ECS) has opened the door to novel therapeutical approaches targeting cancer, pain, anxiety, stress,…
endocannabinoid system
Relevance of Peroxisome Proliferator Activated Receptors in Multitarget Paradigm Associated with the Endocannabinoid System
Abstract Cannabinoids have shown to exert their therapeutic actions through a variety of targets. These include not only the canonical…
Phytocannabinoids—A Green Approach toward Non-Alcoholic Fatty Liver Disease Treatment
Abstract Non-alcoholic fatty liver disease (NAFLD) is the most frequent chronic liver disease in adults in developed countries, with a…
The Complex Interplay between Endocannabinoid System and the Estrogen System in Central Nervous System and Periphery
Abstract The endocannabinoid system (ECS) is a lipid cell signaling system involved in the physiology and homeostasis of the brain…
CB2 Receptor in Microglia: The Guardian of Self-Control
Abstract Microglia are key to maintaining the homeostasis of the brain. These immune cells of the brain can be our…
CannabinEYEds: The Endocannabinoid System as a Regulator of the Ocular Surface Nociception, Inflammatory Response, Neovascularization and Wound Healing
Abstract The endocannabinoid system (ECS) is a complex regulatory system, highly conserved among vertebrates. It has been widely described in…
New Insights Into Peptide Cannabinoids: Structure, Biosynthesis and Signaling
Abstract Classically, the endocannabinoid system (ECS) consists of endogenous lipids, of which the best known are anandamide (AEA) and 2…
Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders
Abstract Though there is limited research confirming the purported topical benefits of cannabinoids, it is certain that cutaneous biology is…
The Immune Endocannabinoid System of the Tumor Microenvironment
Abstract Leukocytes are part of the tumor microenvironment (TME) and are critical determinants of tumor progression. Because of the immunoregulatory…
Can We Treat Neuroinflammation in Alzheimer’s Disease?
Abstract Alzheimer’s disease (AD), considered the most common type of dementia, is characterized by a progressive loss of memory, visuospatial,…