Cannabis and Inflammation in HIV: A Review of Human and Animal Studies
Abstract Persistent inflammation occurs in people with HIV (PWH) and has many downstream adverse effects including myocardial infarction, neurocognitive impairment…
endocannabinoid system
Reversing the Psychiatric Effects of Neurodevelopmental Cannabinoid Exposure: Exploring Pharmacotherapeutic Interventions for Symptom Improvement
Abstract Neurodevelopmental exposure to psychoactive compounds in cannabis, specifically THC, is associated with a variety of long-term psychopathological outcomes. This…
Potassium channels as molecular targets of endocannabinoids
Abstract Endocannabinoids are a group of endogenous mediators derived from membrane lipids, which are implicated in a wide variety of…
Cannabinoids in the landscape of cancer
Abstract Introduction: Cannabinoids are a group of terpenophenolic compounds derived from the Cannabis sativa L. plant. There is a growing…
Early Consumption of Cannabinoids: From Adult Neurogenesis to Behavior
Abstract The endocannabinoid system (ECS) is a crucial modulatory system in which interest has been increasing, particularly regarding the regulation…
From the Clinic to the Laboratory, and Back Again: Investigations on Cannabinoids and Endocannabinoid System Modulators for Treating Schizophrenia
Abstract The present mini-review focuses on animal models of schizophrenia that have explored the effects of cannabidiol (CBD; a non-psychoactive…
Prolonged efavirenz exposure reduces peripheral oxytocin and vasopressin comparable to known drugs of addiction in male Sprague Dawley rats
Abstract Introduction: Several drugs of abuse (DOA) are capable of modulating neurohypophysial hormones, such as oxytocin (OT) and vasopressin (VP),…
Endocannabinoid System in Pregnancy Maintenance and Labor: A Mini-Review
Abstract The endocannabinoid system (ECS) is a cell-signaling system present in multiple organ systems and is an integral part of…
Therapeutic Attributes of Endocannabinoid System against Neuro-Inflammatory Autoimmune Disorders
Abstract In humans, various sites like cannabinoid receptors (CBR) having a binding affinity with cannabinoids are distributed on the surface…
Pro-Inflammatory Cytokines: Potential Links between the Endocannabinoid System and the Kynurenine Pathway in Depression
Abstract Substance use/abuse is one of the main causes of depressive symptoms. Cannabis and synthetic cannabinoids in particular gained significant…