The Effect of Marijuana on the Incidence and Evolution of Male Infertility: A Systematic Review
Abstract Over the past decade, the consumption of marijuana or any other form of cannabis, whether medically, recreationally, or illegally,…
endocannabinoid system
Endocannabinoid System and Tumour Microenvironment: New Intertwined Connections for Anticancer Approaches
Abstract The tumour microenvironment (TME) is now recognised as a hallmark of cancer, since tumour:stroma crosstalk supports the key steps…
Cannabinoid Therapeutics in Chronic Neuropathic Pain: From Animal Research to Human Treatment
Abstract Despite the importance of pain as a warning physiological system, chronic neuropathic pain is frequently caused by damage in…
The Endocannabinoid System as a Pharmacological Target for New Cancer Therapies
Abstract Simple Summary: Cannabinoids have been shown to suppress tumour cell proliferation, tumour invasion, metastasis, angiogenesis, chemoresistance and epithelial-mesenchymal transition…
Cannabinoid Drugs-Related Neuroprotection as a Potential Therapeutic Tool Against Chemotherapy-Induced Cognitive Impairment
Abstract In recent years, and particularly associated with the increase of cancer patients’ life expectancy, the occurrence of cancer treatment…
Major Phytocannabinoids and Their Related Compounds: Should We Only Search for Drugs That Act on Cannabinoid Receptors?
Abstract The most important discoveries in pharmacology, such as certain classes of analgesics or chemotherapeutics, started from natural extracts which…
Hypothalamic endocannabinoids in obesity: an old story with new challenges
Abstract The crucial role of the hypothalamus in the pathogenesis of obesity is widely recognized, while the precise molecular and…
Endocannabinoid System Unlocks the Puzzle of Autism Treatment via Microglia
Abstract Autism spectrum disorder (ASD) is a serious neurodevelopmental disorder and characterized by early childhood-onset impairments in social interaction and…
Cannabinoids: an Effective Treatment for Chemotherapy-Induced Peripheral Neurotoxicity?
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s13311-021-01127-1. Article type: Research Article Keywords: Chemotherapy, Neuropathy, Endocannabinoid…
N-Acyl Dopamines Induce Apoptosis in Endometrial Stromal Cells from Patients with Endometriosis
Abstract Endometriosis is characterized by the formation and development of endometrial tissues outside the uterus, based on an imbalance between…