Abstract Objective: Growth Factor Receptor-Binding Protein 10 (GRB10) is an adaptor protein implicated in tyrosine kinase signaling, yet its pan-cancer…
Abstract Objective: This study aims to analyze the genes that influence PTC progression and investigate the role of MAPK13 in…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-23587-7. Article type: Research Article Keywords: MET, Thyroid cancer,…
Abstract Background: Lung cancer is one of the most prevalent and lethal cancers worldwide, with limited therapeutic options in advanced…
Abstract Pancreatic ductal adenocarcinoma (PDAC) is characterized by aggressive metastasis and poor response to chemotherapy, largely driven by epithelial–mesenchymal transition…
Abstract Background: Papillary thyroid cancer (PTC) is the most common type of thyroid malignancy. While the prognosis of PTC is…
Abstract Purpose: KLK7, also known as Kallikrein 7, is a secreted enzyme classified as a serine protease. Earlier studies have…
Abstract Bone metastasis significantly contributes to the unfavorable prognosis observed in patients with prostate cancer. MYB proto-oncogene like 2 (MYBL2)…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s12943-024-02180-y. Article type: Research Article Keywords: Colorectal cancer, Oxaliplatin…
Abstract Background: The NTRK fusion gene is a rare cancer driver and a typical representative "diamond mutation". Its unique role…