Neuropsychological Consequences of Chronic Drug Use: Relevance to Treatment Approaches
Abstract Heavy use of drugs impacts of the daily activities of individuals in these activities. Several groups of investigators have…
Dorsolateral prefrontal cortex
Endocannabinoids and striatal function: implications for addiction-related behaviours
Abstract Since the identification and cloning of the major cannabinoid receptor expressed in the brain almost 25 years ago research…
The Role of Cannabinoid Transmission in Emotional Memory Formation: Implications for Addiction and Schizophrenia
Abstract Emerging evidence from both basic and clinical research demonstrates an important role for endocannabinoid (ECB) signaling in the processing…
CB1 cannabinoid receptor stimulation during adolescence impairs the maturation of GABA function in the adult rat prefrontal cortex
Abstract Converging epidemiological studies indicate that cannabis abuse during adolescence increases the risk of developing psychosis and prefrontal cortex (PFC)-dependent…
Association of Cannabis Use during Adolescence, Prefrontal CB1 Receptor Signaling, and Schizophrenia
Abstract The cannabinoid receptor 1 (CB1R) is the G-protein coupled receptor responsible for the majority of the endocannabinoid signaling in…
Altered Frontal Cortical Volume and Decision Making in Adolescent Cannabis Users
Abstract Anticipating future outcomes is central to decision making and a failure to consider long-term consequences may lead to impulsive…