DNAJ co-chaperones

November 3, 2023

DNAJB6 mutants display toxic gain of function through unregulated interaction with Hsp70 chaperones

Abstract Molecular chaperones are essential cellular components that aid in protein folding and preventing the abnormal aggregation of disease-associated proteins.…

November 8, 2022

Head-to-tail polymerization by VEL proteins underpins cold-induced Polycomb silencing in flowering control

Abstract Transcriptional silencing through the Polycomb silencing machinery utilizes a “read-write” mechanism involving histone tail modifications. However, nucleation of silencing…

May 17, 2019

Heat shock proteins create a signature to predict the clinical outcome in breast cancer

Abstract Utilizing The Cancer Genome Atlas (TCGA) and KM plotter databases we identified six heat shock proteins associated with survival…