Cannabis use and the sperm epigenome: a budding concern?
Abstract The United States is swiftly moving toward increased legalization of medical and recreational cannabis. Currently considered the most commonly…
DNA methylation
The Epigenetics of the Endocannabinoid System
Abstract The endocannabinoid system (ES) is a cell-signalling system widely distributed in biological tissues that includes endogenous ligands, receptors, and…
Cannabis use is associated with potentially heritable widespread changes in autism candidate gene DLGAP2 DNA methylation in sperm
Abstract Parental cannabis use has been associated with adverse neurodevelopmental outcomes in offspring, but how such phenotypes are transmitted is…
Impacts of cannabinoid epigenetics on human development: reflections on Murphy et. al. ‘cannabinoid exposure and altered DNA methylation in rat and human sperm’ epigenetics 2018; 13: 1208-1221.
Abstract Recent data from the Kollins lab (‘Cannabinoid exposure and altered DNA methylation in rat and human sperm’ Epigenetics 2018;…
Cannabinoid exposure and altered DNA methylation in rat and human sperm
Abstract Little is known about the reproductive effects of paternal cannabis exposure. We evaluated associations between cannabis or tetrahydrocannabinol (THC)…
Cannabis use by women during pregnancy does not influence infant DNA methylation of the dopamine receptor DRD4
Abstract Background: Maternal cannabis use in pregnancy is linked with long-term adverse behavioral outcomes in offspring. Epigenetic processes established in…
Epigenetic Interactions between Alcohol and Cannabinergic Effects: Focus on Histone Modification and DNA Methylation
Abstract Epigenetic studies have led to a more profound understanding of the mechanisms involved in chronic conditions. In the case…
A quantitative epigenetic approach for the assessment of cigarette consumption
Abstract Smoking is the largest preventable cause of morbidity and mortality in the world. Despite the development of numerous preventive…