Abstract Disulfidptosis—a regulated cell death caused by disulfide stress under glucose starvation and high SLC7A11—offers a potential cancer vulnerability, but…
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s12885-025-14246-1. Article type: Research Article Keywords: Pan-cancer, Disulfidptosis, Prognosis,…
Abstract Recent studies have uncovered intriguing connections between Parkinson’s disease (PD) and cancer, two seemingly distinct disease categories. Disulfidptosis has…
Abstract To get a systematic assessment of disulfidptosis-related genes across human cancers and explore the predictive role of disulfidptosis in…
Abstract Objective: The primary objective of this study is to conduct a comprehensive screening and analysis of differentially expressed genes…
Abstract Background: Elevated expression of SLC7A11, in conjunction with glucose deprivation, has revealed disulfidptosis as an emerging cell death modality.…
Abstract Background: Numerous studies have shown a strong correlation between disulfidptosis and various cancers. However, the expression and function of…
Abstract Disulfidptosis was recently reported to be caused by abnormal disulfide accumulation in cells with high SLC7A11 levels subjected to…
Abstract Background: Disulfidptosis is a newly discovered form of regulated cell death. The research on disulfidptosis and tumor progression remains…
Abstract It is well established that the antitoxins of toxin–antitoxin (TA) systems are selectively degraded by bacterial proteases in response…