A Survey of Regulatory Interactions Among RNA Binding Proteins and MicroRNAs in Cancer
Abstract Recent advances in genomics and proteomics generated a large amount of trans regulatory data such as those mediated by…
dietary microRNAs
Identification of microRNAs Targeting the Transporter Associated with Antigen Processing TAP1 in Melanoma
Abstract The underlying molecular mechanisms of the aberrant expression of components of the HLA class I antigen processing and presentation…
Identification of MicroRNA-Related Tumorigenesis Variants and Genes in the Cancer Genome Atlas (TCGA) Data
Abstract MicroRNAs (miRNAs) are a class of small non-coding RNA that can down-regulate their targets by selectively binding to the…
Prognostic lncRNA, miRNA, and mRNA Signatures in Papillary Thyroid Carcinoma
Abstract The current focus in the treatment of papillary thyroid carcinoma (PTC) is tumor progression. The aim of this study…
Papillary Thyroid Carcinoma Variants are Characterized by Co-dysregulation of Immune and Cancer Associated Genes
Abstract Papillary thyroid carcinoma (PTC) variants exhibit different prognosis, but critical characteristics of PTC variants that contribute to differences in…
CMTCN: a web tool for investigating cancer-specific microRNA and transcription factor co-regulatory networks
Abstract Transcription factors (TFs) and microRNAs (miRNAs) are well-characterized trans-acting essential players in gene expression regulation. Growing evidence indicates that…
The Cancer Omics Atlas: an integrative resource for cancer omics annotations
Abstract Background: The Cancer Genome Atlas (TCGA) is an important data resource for cancer biologists and oncologists. However, a lack…
Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context
Abstract Long noncoding RNAs (lncRNAs) are commonly dysregulated in tumors, but only a handful are known to play pathophysiological roles…