Acute effects of different types of cannabis on young adult and adolescent resting-state brain networks
Abstract Adolescence is a time of rapid neurodevelopment and the endocannabinoid system is particularly prone to change during this time.…
Development of the nervous system
Characterization of cannabinoid plasma concentration, maternal health, and cytokine levels in a rat model of prenatal Cannabis smoke exposure
Abstract Cannabis sativa has gained popularity as a “natural substance”, leading many to falsely assume that it is not harmful.…
Microglial cannabinoid receptor type 1 mediates social memory deficits in mice produced by adolescent THC exposure and 16p11.2 duplication
Abstract Adolescent cannabis use increases the risk for cognitive impairments and psychiatric disorders. Cannabinoid receptor type 1 (Cnr1) is expressed…
Medium-throughput zebrafish optogenetic platform identifies deficits in subsequent neural activity following brief early exposure to cannabidiol and Δ9-tetrahydrocannabinol
Abstract In light of legislative changes and the widespread use of cannabis as a recreational and medicinal drug, delayed effects…
Cannabinoids Exacerbate Alcohol Teratogenesis by a CB1-Hedgehog Interaction
Abstract We tested whether cannabinoids (CBs) potentiate alcohol-induced birth defects in mice and zebrafish, and explored the underlying pathogenic mechanisms…
Effects of cannabidiol on brain excitation and inhibition systems; a randomised placebo-controlled single dose trial during magnetic resonance spectroscopy in adults with and without autism spectrum disorder
Abstract There is increasing interest in the use of cannabis and its major non-intoxicating component cannabidiol (CBD) as a treatment…