Skin on Drugs: Psychotropic Compounds in Cutaneous Biology
Abstract Recent evidence reveals that several psychotropic compounds exert significant biological effects on the skin through neurochemical and immunomodulatory pathways.…
Dehusking
Hybrid Cannabis sativa L. inflorescences exert an anti-inflammatory effect through the modulation of MAPK/NF-κB/NLRP3 inflammasome and JAK1/STAT6 pathway in HaCaT cells
Abstract Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease accompanied by severe itching. Reducing mediators of skin inflammation…
Lipidome Complexity in Physiological and Pathological Skin Pigmentation
Abstract Skin pigmentation results from complex cellular interactions and is influenced by genetic, environmental, and metabolic factors. Emerging evidence highlights…
Beak dimensions affect feeding performance within a granivorous songbird species
Abstract Beaks of granivorous songbirds are adapted to dehusk seeds fast and efficiently. This is reflected in the large variety…
Exploring the Biological Activity of Phytocannabinoid Formulations for Skin Health Care: A Special Focus on Molecular Pathways
Abstract Recent advancements have highlighted the potential of cannabis and its phytocannabinoids (pCBs) in skin health applications. These compounds, through…
Lipid Nanoparticle Formulations for the Skin Delivery of Cannabidiol
Abstract Background/Objectives: The aims of this work were to formulate cannabidiol in different lipid carriers for skin delivery after topical…
Oral Cannabidiol for Seborrheic Dermatitis in Patients With Parkinson Disease: Randomized Clinical Trial
Abstract Background: Seborrheic dermatitis (SD) affects 18.6%-59% of persons with Parkinson disease (PD), and recent studies provide evidence that oral…
Cutaneous targets for topical pain medications in patients with neuropathic pain: individual differential expression of biomarkers supports the need for personalized medicine
Abstract Supplemental Digital Content is Available in the Text. Biomarker analysis of postherpetic neuralgia patient skin biopsies demonstrates individual differences…
Release of delta-9-tetrahydrocannabinol from polyvinyl alcohol hydrogels and its safe interaction with human skin fibroblasts
Abstract This study aimed to design a THC-rich hydrogel to deliver cannabis derivatives topically. We developed hydrogels using polyvinyl alcohol…
Evaluating the Mechanism of Cell Death in Melanoma Induced by the Cannabis Extract PHEC-66
Abstract Research suggests the potential of using cannabinoid-derived compounds to function as anticancer agents against melanoma cells. Our recent study…