“In the light of evolution:” keratins as exceptional tumor biomarkers
Abstract Keratins (KRTs) are the intermediate filament-forming proteins of epithelial cells, classified, according to their physicochemical properties, into “soft” and…
data mining
ANXA10 is a prognostic biomarker and suppressor of hepatocellular carcinoma: a bioinformatics analysis and experimental validation
Abstract Liver hepatocellular carcinoma (LIHC) is one of the main cancers worldwide and has high morbidity and mortality rates. Although…
Genomic disparities between cancers in adolescent and young adults and in older adults
Abstract Cancers cause significant mortality and morbidity in adolescents and young adults (AYAs), but their biological underpinnings are incompletely understood.…
Consumer-Generated Discourse on Cannabis as a Medicine: Scoping Review of Techniques
Abstract Background: Medicinal cannabis is increasingly being used for a variety of physical and mental health conditions. Social media and…
The role of toll-like receptors (TLRs) in pan-cancer
Abstract Background: Toll-like receptors (TLRs) are important components of the innate and adaptive immune systems, and abnormal TLR expression has…
Systematic evaluation of the prognostic and immunological role of PDLIM2 across 33 cancer types
Abstract The protein PDLIM2 regulates the stability of various transcription factors and is required for polarized cell migration. However, the…
The pan-cancer landscape of netrin family reveals potential oncogenic biomarkers
Abstract Recent cancer studies have found that the netrin family of proteins plays vital roles in the development of some…
Pan-cancer diagnostic consensus through searching archival histopathology images using artificial intelligence
Abstract The emergence of digital pathology has opened new horizons for histopathology. Artificial intelligence (AI) algorithms are able to operate…
Epigenetic-Mediated Downregulation of Zinc Finger Protein 671 (ZNF671) Predicts Poor Prognosis in Multiple Solid Tumors
Abstract Zinc finger protein 671 (ZNF671) is a member of the largest transcription factor family in the human genome. However,…