Cancer Segmentation by Entropic Analysis of Ordered Gene Expression Profiles
Abstract The availability of massive gene expression data has been challenging in terms of how to cure, process, and extract…
cytokine gene expression
Validation of transcriptome signature reversion for drug repurposing in oncology
Abstract Transcriptome signature reversion (TSR) has been extensively proposed and used to discover new indications for existing drugs (i.e. drug…
Expression of Genes Involved in ABA and Auxin Metabolism and LEA Gene during Embryogenesis in Hemp
Abstract The level of phytohormones such as abscisic acid (ABA) and auxins (Aux) changes dynamically during embryogenesis. Knowledge of the…
Bisphenol A is a carcinogen that induces lipid accumulation, peroxisome proliferator‑activated receptor‑γ expression and liver disease
Abstract Bisphenol (BP) A is an exogenous endocrine disruptor that mimics hormones closely associated with health complications, e.g., obesity and…
Genome-Wide Identification and Expression Analysis of Wall-Associated Kinase (WAK) Gene Family in Cannabis sativa L.
Abstract Wall-associated kinases (WAKs) are receptors that bind pectin or small pectic fragments in the cell wall and play roles…
Bioinformatic analysis of the LCN2–SLC22A17–MMP9 network in cancer: The role of DNA methylation in the modulation of tumor microenvironment
Abstract Several features of cancer cells such as proliferation, invasion, metastatic spreading, and drug resistance are affected by their interaction…
Atypical IκB Bcl3 enhances the generation of the NF-κB p52 homodimer
Abstract The NF-κB family of dimeric transcription factors regulate diverse biological functions. Their cellular expression profiles differ, which lead to…
Assessment of deep learning and transfer learning for cancer prediction based on gene expression data
Abstract Background: Machine learning is now a standard tool for cancer prediction based on gene expression data. However, deep learning…
Comparing Bayesian-Based Reconstruction Strategies in Topology-Based Pathway Enrichment Analysis
Abstract The development of high-throughput omics technologies has enabled the quantification of vast amounts of genes and gene products in…
SYNJ2 is a novel and potential biomarker for the prediction and treatment of cancers: from lung squamous cell carcinoma to pan-cancer
Abstract Background: The roles and clinical values of synaptojanin 2 (SYNJ2) in lung squamous cell carcinoma (LUSC) remain unclear. Methods:…