Pan‐cancer analyses reveal molecular and clinical characteristics of cuproptosis regulators
Abstract Imbalance in copper homeostasis can be lethal. A recent study found that excess copper induces cell death in a…
Cuproptosis
Regulation, genomics, and clinical characteristics of cuproptosis regulators in pan-cancer
Abstract Background: Cuproptosis, a copper-dependent controlled cell death, is a novel form of cell death that differs from known cell…
Pan-cancer genetic analysis of cuproptosis and copper metabolism-related gene set
Abstract Background: A recent paper has revealed a novel cell death pathway, cuproptosis, a programmed cell death based on copper.…
Characterization of the functional effects of ferredoxin 1 as a cuproptosis biomarker in cancer
Abstract Background: Cuproptosis is a recently discovered form of programmed cell death. Ferredoxin 1 (FDX1) is a key gene that…
Ferredoxin 1 is a cuproptosis-key gene responsible for tumor immunity and drug sensitivity: A pan-cancer analysis
Abstract Ferredoxin 1 (FDX1) functions by transferring electrons from NADPH to mitochondrial cytochrome P450 via the ferredoxin reductase and is…
FDX1 expression predicts favourable prognosis in clear cell renal cell carcinoma identified by bioinformatics and tissue microarray analysis
Abstract Ferredoxin 1 (FDX1), an iron-sulphur protein, is responsible for electron transfer in a range of metabolic redox reactions. Clear…
CDKN2A-mediated molecular subtypes characterize the hallmarks of tumor microenvironment and guide precision medicine in triple-negative breast cancer
Abstract Currently, breast cancer (BRCA) has become the most common cancer in the world, whose pathological mechanism is complex. Among…
Pan-cancer analyses confirmed the cuproptosis-related gene FDX1 as an immunotherapy predictor and prognostic biomarker
Abstract Background: The latest research identified cuproptosis as an entirely new mechanism of cell death. However, as a key regulator…
Comprehensive analysis of the potential cuproptosis-related biomarker LIAS that regulates prognosis and immunotherapy of pan-cancers
Abstract Lipoic acid synthetase (LIAS) has been demonstrated to play a crucial role in the progression of cancer. Exploring the…
Comprehensive analyses of cuproptosis-related gene CDKN2A on prognosis and immunologic therapy in human tumors
Abstract Recent studies have identified a novel programmed cell death based on copper, named cuproptosis. However, as an anti-cuproptosis gene,…