Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-11151-2. Article type: Research Article Keywords: Papillary thyroid carcinoma,…
Abstract Background: Clear cell renal cell carcinoma (ccRCC) is a relatively frequently diagnosed form of urological cancer that is highly…
Abstract Cuproptosis was the most enriched type of Programmed Cell Death (PCD) processes in THCA. Cuproptosis was associated with tumor…
Abstract Cuproptosis differs from other forms of cell death, such as apoptosis, necroptosis, and ferroptosis, in its unique molecular mechanisms…
Abstract Breast cancer (BC) is the leading cause of cancer-related mortality among women globally, affecting approximately one-quarter of all female…
Abstract Copper is an important trace element for maintaining key biological functions such as cellular respiration, nerve conduction, and antioxidant…
Abstract Metal regulatory transcription factor 1 (MTF1) has been reported to induce the expression of metallothionein and other genes involved…
Abstract Cancer is widely regarded as a leading cause of death in humans, with colon adenocarcinoma (COAD) ranking among the…
Abstract Background: Cuproptosis is a newly identified form of unprogrammed cell death. As a pivotal metabolic regulator, glutaminase (GLS) has…
Abstract Background: ATP7B is a copper-transporting protein that contributes to the chemo-resistance of human cancer cells. It remains unclear what…