Neuropathology and emerging biomarkers in corticobasal syndrome
Abstract Corticobasal syndrome (CBS) is a clinical syndrome characterised by progressive asymmetric limb rigidity and apraxia with dystonia, myoclonus, cortical…
corticobasal degeneration
Delayed Detection of Hydrocephalus following Mildly Traumatic Subarachnoid Hemorrhage in Corticobasal Degeneration: A Case Report
Abstract A 65-year-old woman presented with slowly progressive aphasia with gait disturbance associated with parkinsonism. She experienced a fall that…
A Case of Pathologically Confirmed Corticobasal Degeneration Initially Presenting as Progressive Supranuclear Palsy Syndrome
Abstract Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) overlap clinically with parkinsonism or extrapyramidal signs and pathologically with tauopathy.…
Pathologically Verified Corticobasal Degeneration Mimicking Richardson’s Syndrome Coexisting with Clinically and Radiologically Shunt‐Responsive Normal Pressure Hydrocephalus
Abstract Background: Normal pressure hydrocephalus (NPH) manifests as gait instability, cognitive impairment, and urinary incontinence. This clinical triad of NPH…
The Non-motor Symptoms, Disability Progression, and Survival Analysis of Atypical Parkinsonism: Case Series from Eastern India and Brief Review of Literature
Abstract Objective The objectives of this study are (1) to describe the non-motor profile, the motor disability progression, and survival…
Brainstem atrophy is linked to extrapyramidal symptoms in frontotemporal dementia
Abstract Extrapyramidal (EP) symptoms are a known feature in a subpopulation of patients with behavioral variant frontotemporal dementia (bvFTD). Concomitant…
Temporal Progression Patterns of Brain Atrophy in Corticobasal Syndrome and Progressive Supranuclear Palsy Revealed by Subtype and Stage Inference (SuStaIn)
Abstract Differentiating corticobasal degeneration presenting with corticobasal syndrome (CBD-CBS) from progressive supranuclear palsy with Richardson’s syndrome (PSP-RS), particularly in early…
Structural mapping techniques distinguish the surfaces of fibrillar 1N3R and 1N4R human tau
Abstract The rigid core of intracellular tau filaments from Alzheimer’s disease (AD), Pick’s disease (PiD), and Corticobasal disease (CBD) brains…
Dissecting the Binding Profile of PET Tracers to Corticobasal Degeneration Tau Fibrils
Abstract Alzheimer’s disease and primary tauopathies are characterized by the presence of tau pathology in brain. Several tau positron emission…
Deep learning‐based model for diagnosing Alzheimer’s disease and tauopathies
Abstract Aims: This study aimed to develop a deep learning‐based model for differentiating tauopathies, including Alzheimer’s disease (AD), progressive supranuclear…