Abstract Background: The three-prime repair exonuclease 1, TREX1, degrades cytosolic DNA to prevent aberrant immune activation. Its inactivation results in…
Abstract The NUMB gene encodes a conserved adaptor protein with roles in asymmetric cell division and cell fate determination. First…
Abstract NUMB has been initially identified as a critical cell fate determinant that modulates cell differentiation via asymmetrical partitioning during…
Keywords: TME, tumor microenvironment, CAF, cancer-associated fibroblasts, EMT, epithelial-mesenchymal transition, DLBC, diffuse large B-cell lymphoma, TCGA, The Cancer Genome Atlas,…