Distinctive chromosomal, mutational and transcriptional profiling in colon versus rectal cancers
Abstract Background: Colorectal cancer (CRC) encompasses tumors arising in the colon (CC) and rectum (RC), often treated as a single…
Consensus molecular subtypes
Identification of cancer-associated fibroblast subtypes and prognostic model development in breast cancer: role of the RUNX1/SDC1 axis in promoting invasion and metastasis
Abstract Graphical abstract: Supplementary Information: The online version contains supplementary material available at 10.1007/s10565-024-09950-w. Article type: Research Article Keywords: Cancer-associated…
Tumor-immune hybrid cells evade the immune response and potentiate colorectal cancer metastasis through CTLA4
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s10238-024-01515-9. Article type: Research Article Keywords: Circulating hybrid cells,…
IL4I1: a novel molecular biomarker represents an inflamed tumor microenvironment and precisely predicts the molecular subtype and immunotherapy response of bladder cancer
Abstract Introduction: IL4I1, also known as Interleukin-4-induced gene 1, is an enzyme that can modulate the immune system by acting…
Overexpression of MTHFD2 represents an inflamed tumor microenvironment and precisely predicts the molecular subtype and immunotherapy response of bladder cancer
Abstract Introduction: Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2), whose aberrant expression is common in cancers, has recently been identified as a potential…
Oncogenic signaling pathway dysregulation landscape reveals the role of pathways at multiple omics levels in pan-cancer
Abstract Dysregulation of signaling pathways plays an essential role in cancer. However, there is not a comprehensive understanding on how…
Comprehensive analysis of ZFPM2-AS1 prognostic value, immune microenvironment, drug sensitivity, and co-expression network: from gastric adenocarcinoma to pan-cancers
Abstract Background: ZFPM2-AS1, as an oncogenic lncRNA, plays an essential role in the progression of several tumors. However, the prognostic…