Anti-tau antibodies targeting a conformation-dependent epitope selectively bind seeds
Abstract Neurodegenerative tauopathies are caused by the transition of tau protein from a monomer to a toxic aggregate. They include…
conformation
Novel Conformation-Dependent Tau Antibodies Are Modulated by Adjacent Phosphorylation Sites
Abstract Tau proteins within the adult central nervous system (CNS) are found to be abnormally aggregated into heterogeneous filaments in…