Computational biology and bioinformatics

January 28, 2025

Programmed cell death-related gene IL20RA facilitates tumor progression and remodels tumor microenvironment in thyroid cancer

Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-87059-8. Article type: Research Article Keywords: Programmed cell death,…

January 25, 2025

Comprehensive pan-cancer analysis reveals NTN1 as an immune infiltrate risk factor and its potential prognostic value in SKCM

Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-85444-x. Article type: Research Article Keywords: NTN1, Pan-cancer, Biomarker,…

January 7, 2025

Comprehensive analysis of inhibin-β A as a potential biomarker for gastrointestinal tract cancers through bioinformatics approaches

Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-024-72679-3. Article type: Research Article Keywords: INHBA Inhibin-β A,…

December 30, 2024

ACTN1 promotes cell invasion, migration, and EMT in thyroid cancer and is associated with immune infiltration

Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-024-83719-3. Article type: Research Article Keywords: Thyroid cancer, ACTN1,…

December 30, 2024

DCLRE1B as a novel prognostic biomarker associated with immune infiltration: a pancancer analysis

Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-024-80603-y. Article type: Research Article Keywords: DCLRE1B, Pancancer, Prognostic…

December 28, 2024

Pan-cancer association of a mitochondrial function score with genomic alterations and clinical outcome

Abstract Mitochondria are pivotal in cellular energy metabolism and have garnered significant attention for their roles in cancer progression and…

November 16, 2024

Pan-cancer analysis of oncogenic role of CEP55 and experiment validation in clear cell renal cell carcinoma

Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-024-80057-2. Article type: Research Article Keywords: CEP55, ccRCC, Pan-cancer…

November 6, 2024

A pan-cancer study of ADAM9’s immunological function and prognostic value particularly in liver cancer

Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-024-76049-x. Article type: Research Article Keywords: ADAM9, Biomarker, Immune…

October 25, 2024

Discovery of Jaspamycin from marine-derived natural product based on MTA3 to inhibit hepatocellular carcinoma progression

Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-024-75205-7. Article type: Research Article Keywords: MTA3, Pan-cancer, Hepatocellular…

October 15, 2024

Pan-cancer and single-cell analysis reveal dual roles of lymphocyte activation gene-3 (LAG3) in cancer immunity and prognosis

Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-024-74808-4. Article type: Research Article Keywords: LAG3, Immune checkpoint,…