Multi-omics driven computational framework for cancer molecular subtype classification
Abstract Cancer molecular subtype classification is an essential component of precision oncology which provides insights into cancer prognosis and guides…
comparative oncology
METTL3-mediated m6A modification of TACSTD2 mRNA inhibits papillary thyroid cancer progression by activating the TNF signaling and blocking epithelial–mesenchymal transition
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-30448-w. Article type: Research Article Keywords: Papillary thyroid cancer,…
Multi‐Omics Analysis and Experimental Validation Identify RAD51 as a Key Biomarker in OSCC
Abstract Oral squamous cell carcinoma (OSCC) is an aggressive malignancy associated with high morbidity and mortality. RAD51 recombinase (RAD51), a…
Management of Chemotherapy-Induced Peripheral Neuropathy (CIPN) in Oncologic Patients—A New Promise? Preliminary Results
Abstract Simple Summary: Chemotherapy-Induced Peripheral Neuropathy (CIPN) is a well-known condition among oncologic patients. Up to 100% of oncologic patients…
Single-cell transcriptome analysis reveals the potential heterogeneous mechanism of CD8+ T cell immune dysfunction in thyroid cancer
Abstract Anaplastic thyroid cancer (ATC) and papillary thyroid carcinoma (PTC) exhibit significant differences in clinical behavior and immune microenvironments, particularly…
Comprehensive bioinformatics analysis reveals prognostic significance and immunological roles of WNT gene family in breast cancer
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-13315-6. Article type: Research Article Keywords: WNTs, Breast cancer,…
Cannabis Stigma and Symptom Management Considerations in Cancer Survivors: A Mixed-Methods Exploration of Patient Perspectives
Abstract Purpose.: This study aims to assess perceived stigma among CS who use or consider use of cannabis. Methods.: This…
Multidimensional pan cancer analysis of the sodium induced cell death gene TRPM4
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-15082-w. Article type: Research Article Keywords: TRPM4, Sodium-induced cell…
ITGAV as a promising diagnostic, immunological, and prognostic biomarker in pan-cancer
Abstract Integrin αV (ITGAV) plays a key role in cell adhesion, migration, and immune regulation, and is implicated in tumor…
Analysis of the prognostic and immune role of MCM6 in pan-cancer and experimental validation in lung adenocarcinoma cells
Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-13598-9. Article type: Research Article Keywords: MCM6, Pan-cancer, Prognosis,…