Antiproliferative Effects of Cannabinoids and Cisplatin in Cervical Cancer Cells
Abstract Introduction: Cervical cancer remains a leading cause of cancer‐related mortality among women globally, particularly in low‐ and middle‐income countries.…
Combination therapy
Synergistic Anticancer Activity of Cannabinoids and Terpenes Against Triple-Negative Breast Cancer Resistance
Abstract Triple-negative breast cancer (TNBC) remains highly aggressive and refractory to conventional treatments, underscoring the need for novel combination strategies.…
Reawakening Differentiation Therapy in Acute Myeloid Leukemia: A Comprehensive Review of ATRA-Based Combination Strategies
Abstract All-trans retinoic acid (ATRA) is an established differentiation therapy for acute promyelocytic leukemia (APL), but its effect in other…
Cytotoxicity of Cannabinoids in Combination with Traditional Lymphoma Chemotherapeutic Drugs Against Non-Hodgkin’s Lymphoma
Abstract Background: Cannabinoids (CBs) are FDA-approved for mitigating chemotherapy-induced side effects such as pain, nausea, and loss of appetite. Beyond…
Enhanced Antibacterial and Anti-Inflammatory Activities of the Combination of Cannabis sativa and Propolis Extracts: An In Vitro Study
Abstract Sore throat, commonly associated with pharyngitis and tonsillitis, is primarily caused by bacterial pathogens. Conventional therapies rely on antibiotics…
A comprehensive review of alkaloids in cancer therapy: focusing on molecular mechanisms and synergistic potential of piperine in colorectal cancer
Abstract Alkaloids exhibit a wide range of anticancer activities, including the induction of apoptosis, regulation of autophagy, arrest of the…
The potential role of cannabidiol (CBD) in lung cancer therapy: a systematic review of preclinical and clinical evidence
Abstract Background: Lung cancer is one of the most prevalent and lethal cancers worldwide, with limited therapeutic options in advanced…
Cannabidiol Enhances the Therapeutic Efficacy of Olsalazine and Cyclosporine in a Murine Model of Colitis
Abstract Current therapies for inflammatory bowel disease (IBD), such as olsalazine and cyclosporine, often exhibit limited long-term efficacy and are…
Cannabidiol (CBD) as a potential therapeutic agent for liver cancer: a comprehensive review of current evidence
Abstract Hepatocellular carcinoma (HCC) is a major cause of cancer-related mortality with limited treatment options. Cannabidiol (CBD), a non-psychoactive compound…
Licofelone, a Dual COX/LOX Inhibitor, Ameliorates Paclitaxel-Induced Mechanical Allodynia in Rats in a Cannabinoid Receptor-Dependent Manner
Abstract The use of paclitaxel as a chemotherapeutic drug is limited by the development of dose-dependent paclitaxel-induced neuropathic pain (PINP).…