Exploring e-psychonauts perspectives towards cocaine effects and toxicity
Abstract Background: According to the World Drug Report, cocaine is the second most used drug globally after cannabis. Online discussion…
cocaine
Regulation of glutamate homeostasis in the nucleus accumbens by astrocytic CB1 receptors and its role in cocaine-motivated behaviors
Abstract Cannabinoid type 1 receptors (CB1Rs) orchestrate brain reward circuitry and are prevalent neurobiological targets for endocannabinoids and cannabis in…
Depression and Cognitive Impairment in a Spanish Sample of Psychoactive Substance Users Receiving Mental Health Care
Abstract (1) Background: Numerous studies state that the abuse of psychoactive substances produces cognitive, emotional and behavioral disorders. The aim…
Maternal Smoking, Alcohol and Recreational Drug Use and the Risk of SIDS Among a US Urban Black Population
Abstract Background: Rates of sudden infant death syndrome (SIDS) are twice as high among Black infants compared to white infants…
Transient Neurogenic Bowel Dysfunction in a Case of Cocaine-Induced Spinal Cord Infarction
Abstract A 23-year-old male presented to the hospital with altered mental status (AMS) and hypoglycemia requiring admission to the ICU.…
Driving under the influence of drugs: Correlation between blood psychoactive drug concentrations and cognitive impairment. A narrative review taking into account forensic issues
Abstract Driving under the influence of alcohol has been shown to increase the risk of involvement in road traffic collisions…
Δ 9-Tetrahydrocannabinol During Adolescence Reprograms the Nucleus Accumbens Transcriptome, Affecting Reward Processing, Impulsivity, and Specific Aspects of Cocaine Addiction-Like Behavior in a Sex-Dependent Manner
Abstract Background: Cannabis exposure during adolescence is associated with emotional and motivational alterations that may entail an enhanced risk of…
Cannabidiol Produces Distinct U-Shaped Dose-Response Effects on Cocaine-Induced Conditioned Place Preference and Associated Recruitment of Prelimbic Neurons in Male Rats
Abstract Background: Cannabidiol (CBD) has received attention for the treatment of substance use disorders. In preclinical models of relapse, CBD…
Effects of illicit drugs on structural and functional impairment of testis, endocrinal disorders, and molecular alterations of the semen
Abstract Illicit drug use is growing among young people, which is one of the major problems in today’s society that…
Prolonged efavirenz exposure reduces peripheral oxytocin and vasopressin comparable to known drugs of addiction in male Sprague Dawley rats
Abstract Introduction: Several drugs of abuse (DOA) are capable of modulating neurohypophysial hormones, such as oxytocin (OT) and vasopressin (VP),…