Comprehensive Analysis of Co-Mutations Identifies Cooperating Mechanisms of Tumorigenesis
Abstract Simple Summary: Somatic mutations are one of the most important causal factors of cancers. In this study, we show…
co-mutation
RB1 and TP53 co-mutations correlate strongly with genomic biomarkers of response to immunity checkpoint inhibitors in urothelial bladder cancer
Abstract Background: Muscle invasive urothelial bladder carcinoma (MIBC) present RB1 and TP53 somatic alterations in a variable percentage of tumors…