Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-31312-7. Article type: Research Article Keywords: Polymorphism, Molecular variance,…
Abstract Background/Objectives: The heterogeneity of the tumor immune microenvironment is a key determinant of tumor oncogenesis. This study aims to…
Abstract Unsupervised learning, particularly clustering, plays a pivotal role in disease subtyping and patient stratification, especially with the abundance of…
Abstract Clusterin (CLU) is a chaperone-like protein that has been demonstrated to have a direct relationship with cancer occurrence, progression,…
Abstract Background: Psychedelics represent a unique subset of psychoactive substances that can induce an aberrant state of consciousness principally via…
Abstract Background: Emerging evidence has revealed that some long intergenic non-coding RNAs (lincRNAs) are likely to form clusters on the…
Abstract Simple Summary: Cancer metastasis is considered to be one of the most significant causes of cancer morbidity, accounting for…
Abstract Background: microRNA (miRNA) is a short RNA (~ 22 nt) that regulates gene expression at the posttranscriptional level. Aberration…
Abstract Background: Transcription factors are essential regulators of gene expression and play critical roles in development, differentiation, and in many…
Abstract Background: One major goal of large-scale cancer omics study is to identify molecular subtypes for more accurate cancer diagnoses…